My answer is : Yes.
How can confirm your BizTalk version that which is?
There are two ways:
First, look up your register information below
Second, look up Add Remove Programs list, search "BizTalk"
I was shocked and thought I couldn't upgrade.
Fortunately, I found a Sandro article on Google
https://blog.sandro-pereira.com/2018/09/21/biztalk-server-repair-installation-error-please-insert-the-disk-1/
Just put the all installation files in the local driver and re-install it again.
Finally, you can check below
register information:















































